John Burke may refer to: - John Bernard Burke (1814–1892), British genealogist
- John Burke (artist) (1946–2006), Irish artist
- John Burke (author) (born 1922), English writer of novels and short stories
- John Burke (colonel) (1838–1914), officer in the Union Army during the American Civil War
- John Burke (genealogist) (1787–1848), Irish genealogist, founder of Burke's Peerage
- John Burke (spy) (1830–1871), Confederate spy in the American Civil War
- John J. Burke (1875-1936), Paulist priest and editor of the Catholic World from 1903 to 1922.
- John P. Burke, President of Trek Bicycle Corporation
- John R. Burke (1924–1993), U.S. ambassador to Guyana
- John Roland Burke, USMC sniper who received the Navy Cross for his actions during the Vietnam War
- Johnny Burke, (1851–1930), Newfoundland songwriter
- Johnny Burke (lyricist) (1908–1964), American songwriter
- Athletes
- John Burke (1900s pitcher) (1877–1950), U.S. baseball player for the New York Giants
- John Burke (1990s pitcher) (born 1970), U.S. baseball player for the Colorado Rockies and the University of Florida
- John Burke (American football) (born 1971), played for the New England Patriots, New York Jets and San Diego Chargers
- John Burke (footballer), Irish footballer from Tipperary
- John Burke (footballer born 1957), Irish footballer from Dublin
- Johnny Burke (footballer) (1911–1987), Irish footballer
- John Burke (rugby league), rugby league footballer of the 1970s for Leeds, Keighley, South Sydney Rabbitohs, and Wakefield Trinity
- Jack Burke, Jr. (born 1923), full name John Burke, American golfer
- Politicians
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