Jesenice may refer to:

• Jesenice, a town and municipality in northwest Slovenia
• Jesenice, a village in the Brežice municipality in southeast Slovenia, near the border with Croatia
• Jesenice u Prahy, a town in the Prague-West District of the Czech Republic
• Jesenice, a village in the Rakovník District of the Czech Republic
• Jesenice, a village in the Příbram District of the Czech Republic
• Jesenice, a collective name for the settlements Krilo, Orij, and Suhi Potok, on the Omiš riviera in Croatia

The placenames refer to either of the two meanings of the South Slavic word "jesen": "ash [tree]" and "autumn."

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