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Jeremy Sanders FRS (born in London, 3rd May 1948),[1] is a British chemist who is known for his contributions to many fields including NMR spectroscopy and supramolecular chemistry. He has been Head of the School of Physical Sciences at the University of Cambridge since 2009; he has also been Deputy Vice-Chancellor since 2006, responsible for overseeing the 800th Anniversary celebrations.


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[edit] Biography

Educated in London at Southmead and Wandsworth Schools, he then studied chemistry at Imperial College, London where he graduated with a B.Sc. in 1969 and was awarded the Edmund White Prize. During 1969-72 he carried out his PhD studies on lanthanide shift reagents at the University of Cambridge (Churchill College) supervised by Dudley Williams.[2]

Elected a Fellow of Christ's College in 1972, he spent a postdoctoral year in the Pharmacology Department, Stanford University, before returning to Cambridge to become a Demonstrator in Chemistry. He was promoted to Lecturer (1978), Reader (1992) and then Professor (1996). He was Head of the Chemistry Department 2000-2006.

He was Chair, from 2004-2008, of sub-panel 18 (Chemistry) for the UK 2008 Research Assessment Exercise.

[edit] Scientific Contributions

NMR Spectroscopic achievements include the first complete analyses of the proton spectra of steroids through the pioneering use of NOEs and two-dimensional techniques,[3] and new understanding of the biophysical chemistry in vivoof microbial storage polymers.[4]

In supramolecular chemistry, his porphyrin systems have led to one of the first experimental verifications of the predicted Marcus 'inverted region',[5] and the standard model (with Chris Hunter) of aromatic π-π interactions.[6] He has used the coordination chemistry of Zn, Sn, Ru, Rh and Al oligoporphyrins [3] to create new complex systems,[7] to develop new templated approaches in synthesis,[8] and to engineer the acceleration of intermolecular reactions within host cavities.[9]

Since the mid-1990s he has been in the forefront (with Jean-Marie Lehn of developing Dynamic covalent chemistry and Supramolecular chemistry [4] and the closely-related dynamic combinatorial chemistry.[10] In dynamic covalent chemistry, the most stable accessible product of a mixture is formed using thermodynamically-controlled reversible reactions; in dynamic combinatorial chemistry a template is used to direct the synthesis of the molecule that best stabilises the template. In each case unpredictable molecules may be discovered that would not be designed or could not be prepared by conventional chemistry. These approaches have been particularly successful in preparing unpredictable Catenanes.[11]

Sanders has also recently discovered helical supramolecular nanotubes capable of binding C60 Fullerene and other guests.[12]

[edit] Awards and Honours

  • 1975 - Meldola Medal and Prize, Royal Institute of Chemistry
  • 1981 - Hickinbottom Award, Royal Society of Chemistry, Royal Society of Chemistry
  • 1984 - Pfizer Academic Award (for work on nuclear Overhauser effect), Royal Society of Chemistry
  • 1988 - Pfizer Academic Award (for work on in vivo NMR), Royal Society of Chemistry
  • 1994 - Josef Loschmidt Prize, Royal Society of Chemistry
  • 1995 - Elected Fellow of the Royal Society (FRS), Fellows of the Royal Society
  • 1996 - Pedler Medal and Prize, Royal Society of Chemistry
  • 2002 - Visiting Fellow, Japan Society for Promotion of Science, JSPS
  • 2003 - Izatt-Christensen Award in Macrocyclic Chemistry (U.S.A.)
  • 2009 - Davy Medal, The Royal Society "for his pioneering contributions to several fields, most recently to the field of dynamic combinatorial chemistry at the forefront of supramolecular chemistry"
  • 2011 - President (Vice-President 2010), Bürgenstock Conference, Switzerland[13]

[edit] References

  1. ^ For a full CV and publication list see [1]
  2. ^ Nature, 1972, 240, 285-390
  3. ^ J. Am. Chem. Soc., 1980, 102, 5703-5711
  4. ^ J. Biol. Chem., 1989, 264, 3286-3291; J. Am. Chem. Soc., 1994, 116, 2695-2702
  5. ^ Chemical Physics, 1986, 104, 315-324
  6. ^ J. Am. Chem. Soc., 1990, 112, 5525-5534. This paper has over 2300 citations: see J. Am. Chem. Soc., 2003, 125, 1-8. DOI: 10.1021/ja021403x
  7. ^ The Porphyrin Handbook; Ed. K. M. Kadish, K. M. Smith, R. Guilard, Academic Press, 2000, vol 3, 347; Inorg. Chem., 2001, 40, 2486; Inorg. Chem., 2008, 47, 87
  8. ^ Accounts Chem. Res., 1993, 26, 469
  9. ^ New J. Chem., 1998, 22, 493-502
  10. ^ Angew. Chemie Intl. Edn., 2002, 41, 898; Chemical Reviews, 2006, 106, 3652
  11. ^ Science, 2005, 308, 667; Proc. Natl. Acad. Sci. USA, 2009, 106, 10466
  12. ^ Angew. Chemie Intl. Edn., 2007, 46, 2338; Faraday Transactions, 2009, DOI: 10.1039/b907538k
  13. ^ [2]





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