Jeremiah Langhorne (died 1742) was a prominent landowner and jurist in colonial Pennsylvania. He is the namesake of present-day Langhorne, Pennsylvania, which adopted his name in 1876, and neighboring Langhorne Manor.

A Quaker, Langhorne settled with his family in Bucks County in 1684. Records show that he purchased 7,200 acres (29 km²) there in 1724. He represented Bucks County in the Assembly, of which he served twice as Speaker. He was a justice of the Pennsylvania Supreme Court from 1726, and served as chief justice from 1739 until his death in 1742.

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