For other Princesses of Asturias named Isabella, see Isabella, Princess of Asturias (disambiguation)

Princess Isabella with her mother, Queen Isabella II

Infanta Isabella, Princess of Asturias (1851–1931), was twice the recognized heir presumptive to the throne of Spain. She was invariantly called "Princesa" in Spain, as the eldest daughter and a holder or formerholder of Asturias, her younger sisters being more usually called with the prefix "Infanta".

She was born as the 2nd eldest surviving child of the then-reigning Queen Isabella II of Spain, from her marriage with her first cousin and king consort, Francis of Spain.

In the turmoiled age of Carlist uprisings and sporadic civil war, Isabella was immediately recognized as the heir to her mother's throne, by granting her the traditional crown-princely title of Asturias.

When her younger brother, the future Alfonso XII of Spain was born in 1857, young Isabella moved to be the second-in-line to the throne, the boy becoming Prince of Asturias.

When Alfonso ascended the throne in 1875, and had not yet any own children, the 24-year old Isabella returned to the position of heiress-presumptive. This she lost finally in 1880 upon the birth of Alfonso's first child, Infantia Marie Louise of Spain, the next Princess of Asturias.

Isabella was married in 1868 to her mother's and father's first cousin, Prince Gaetan, Count of Girgenti (1846–71). He was created Infante of Spain. Princess Isabella was reportedly very popular and respected in Madrid. Isabella died, at 79, in exile in France soon after her nephew Alfonso XIII had lost the throne.

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Ferdinand VII of Spain  • Carlos, Count of Molina  • Maria Isabella, Queen of the Two Sicilies  • Maria Teresa  • Felipe Maria  • Francisco de Paula Grandchildren Carlos, Count of Montemolin  • Juan, Count of Montizón  • Fernando  • Isabella II of Spain  • Maria Luisa Fernanda, Duchess of Montpensier  • Francisco de Asis  • Isabel  • Francis, Duke of Cádiz  • Henry, Duke of Seville  • Luisa, Duchess of Moscoso  • Duarte Felipe  • Josefina  • Teresa  • Fernando  • Maria Cristina, Infanta of Portugal  • Amelia Philippina, Princess Adalbert of Bavaria   Ferdinand VII of Spain Spouse(s) HRH Princess Maria Antonia of Naples and Sicily*  • HRH Infanta Maria Isabel of Portugal  • HH Princess Maria Josepha of Saxony  • HRH Princess Maria Christina of the Two Sicilies* Children Isabella II of Spain  • Maria Luisa Fernanda, Duchess of Montpensier  •   Isabella II of Spain Spouse(s) HRH Infante Francis, Duke of Cadiz Children Ferdinand, Prince of Asturias  • Isabella, Princess of Asturias  • Maria Cristina  • Alfonso XII of Spain  • Maria de la Concepcion  • Maria de Pilar  • María de la Paz, Princess Ludwig of Bavaria  • Francisco de Asis  • Eulalia, Duchess of Galliera   Alfonso XII of Spain Spouse(s) HRH :Princess Mercedes d'Orléans  • HI&RH Archduchess Maria Christina of Austria Children Mercedes, Princess of Asturias  • Maria Teresa, Princess and Duchess of Bavaria  • Alfonso XIII of Spain Grandchildren Alfonso, Duke of Calabria*  • Fernando, Prince of Bourbon-Two Sicilies  • Isabella Alfonsa, Princess of Bourbon-Two Sicilies  • Alfonso, Prince of Asturias  • Jaime, Duke of Segovia  • Beatriz, Princess of Civitella-Cesi  • Ferdinand  • Maria Cristina, Countess of Marone  • Juan, Count of Barcelona  • Gonzalo Great grandchildren Teresa, Princess of Bourbon-Two Sicilies  • Carlos, Duke of Calabria*  • Inés Maria, Princess of Bourbon-Two Sicilies  • Alfonso, Duke of Anjou and Cádiz  • Gonzalo, Duke of Aquitaine  • Pilar, Duchess of Badajoz  • Juan Carlos I of Spain  • Margarita, 2nd Duchess of Hernani  • Alfonso   Alfonso XIII of Spain Spouse(s) HSH Victoria Eugenie of Battenberg Children Alfonso, Prince of Asturias  • Jaime, Duke of Segovia  • Beatriz, Princess of Civitella-Cesi  • Ferdinand  • Maria Cristina, Countess of Marone  • Juan, Count of Barcelona  • Gonzalo Grandchildren Alfonso, Duke of Anjou and Cádiz  • Gonzalo, Duke of Aquitaine  • Pilar, Duchess of Badajoz  • Juan Carlos I of Spain  • Margarita, 2nd Duchess of Hernani  • Alfonso   Juan Carlos I of Spain Spouse(s) HRH Princess Sophia of Greece and Denmark Children Infanta Elena, Duchess of Lugo  • Infanta Cristina, Duchess of Palma de Mallorca  • Felipe, Prince of Asturias Grandchildren Infanta Leonor of Spain  • Infanta Sofía of Spain *also a Prince or Princess of the Two Sicilies **also an Archduchess of Austria ***both