Ileocecal valve:
The ileocecal valve is a sphincter muscle situated at the junction of the small intestine (ileum) and the large intestine. Its critical function is to limit the reflux of colonic contents into the ileum.[1]
Functionally, roughly two litres of fluid enters the colon daily through the ileocecal valve.
[edit] Histology
The histology of the ileocecal valve shows an abrupt change in the villous pattern which is found in small intestinal mucosa, to the glandular pattern found in colonic mucosa.
At the ileocecal valve, there is also thickening of the muscularis mucosa, which is the smooth muscle tissue found beneath the mucosal layer of the digestive tract.
There is also a variable amount of lymphatic tissue found at the valve.[2]
[edit] Clinical significance
During colonoscopy, the ileocecal valve is used, along with the appendiceal orifice, in the identification of the cecum. This is important, as it indicates that a complete colonoscopy has been performed. The ileocecal valve is typically located on the last fold before entry into the cecum, and can be located from the direction of curvature of the appendiceal orifice, in what is known as the bow and arrow sign.[3]
Intubation of the ileocecal valve is typically performed in colonoscopy to evaluate the distal, or lowest part of the ileum. Small bowel endoscopy can also be performed by double-balloon enteroscopy through intubation of the ileocecal valve.[4]
[edit] Pathology
Tumours of the ileocecal valve are rare, but have been reported in the literature.[5][6]
[edit] Etymology
It was discovered by the Dutch physician Nicolaes Tulp (1593-1674), and thus it is sometimes known as Tulp's valve.
[edit] References
- ^ Barret KE. "Lange Gastrointestinal Physiology". The McGraw-Hill Companies, 2006.
- ^ Burkitt HG, Young B, Heath JW. Wheater's Functional Histology: a text and colour atlas. Churchill Livingstone, London, 1993.
- ^ Cotton PB, Williams CB. Practical Gastrointestinal Endoscopy Blackwell Publishers, London, 1996
- ^ Ross AS, Waxman I, Semrad C, Dye C. Balloon-assisted intubation of the ileocecal valve to facilitate retrograde double-balloon enteroscopy. Gastrointest Endosc. 2005 Dec;62(6):987-8. PMID 16301054
- ^ Yoruk G, Aksoz K, Buyrac Z, Unsal B, Nazli O, Ekinci N. Adenocarcinoma of the ileocecal valve: report of a case. Turk J Gastroenterol. 2004 Dec;15(4):268-9. PMID 16249985
- ^ Song HJ, Ko BM, Cheon YK, Ryu CB, Lee JS, Lee MS, Shim CS. Isolated ileocecal lymphoma. Gastrointest Endosc. 2005 Feb;61(2):293-4. PMID 15729248
[edit] External links
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![[Item]: Valve only [Additional Info]: Medline Gauges and Parts Are Tested To Ensure the Most Accurate Results. Medline gauges are tested above government standards that check for accuracy, calibration and life of the gauge. The extensive testing and com](http://ecx.images-amazon.com/images/I/1187AMG06CL._SL75_.jpg "[Item]: Valve only [Additional Info]: Medline Gauges and Parts Are Tested To Ensure the Most Accurate Results. Medline gauges are tested above government standards that check for accuracy, calibration and life of the gauge. The extensive testing and com")
![[Item]: Lopez Valve [Additional Info]: Lopez Valve Helps Protect Health Care Workers From Exposure to Bodily Fluids. This Y-port adapter allows for irrigation or delivery of medications without removing the feeding set connector from feeding tube. For n](http://ecx.images-amazon.com/images/I/210KZY7TYJL._SL75_.jpg "[Item]: Lopez Valve [Additional Info]: Lopez Valve Helps Protect Health Care Workers From Exposure to Bodily Fluids. This Y-port adapter allows for irrigation or delivery of medications without removing the feeding set connector from feeding tube. For n")