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The Hot 100 Singles Sales (also known as Singles Sales) is a chart released weekly by Billboard magazine in the United States. It measures sales of commercial singles and is one of three component charts, along with the Hot 100 Airplay and the Hot Digital Songs, that determine the chart positions of singles on the Billboard Hot 100 chart. With the decline in sales of physical singles in the US, songs that become number one on this chart often do not even chart on the Hot 100.

With the introduction of The Pop 100, the Hot 100 Singles Sales chart information has been utilized for compiling both the Hot 100 and Pop 100 – thus a recent slight name change to "Singles Sales" (to show its uses for both charts). However, the name is still in a transition period and it has not been confirmed if the change is permanent.

Elton John has the record for most singles sold in a week, with 3.4 million copies of "Candle in the Wind 1997/Something about the Way You Look Tonight" sold the week of October 11, 1997.

Indie band Bright Eyes was the last band to have two songs occupy the top 2 spots, in 2004 with the singles "Lua" from the album I'm Wide Awake, It's Morning and "Take It Easy (Love Nothing)" from the album Digital Ash in a Digital Urn.