Hesychius (Greek for "calm one"), may refer to:

• Hesychius of Alexandria, lexicographer
• St. Hesychius of Cazorla, saint, martyr, and bishop
• Hesychius of Jerusalem, presbyter and exegete
• Hesychius of Sinai, hieromonk and Byzantine author
• Hesychius of Antioch
• Hesychius of Miletus, chronicler

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