HMG-CoA
IUPAC name	(9R,21S)-1-[(2R,3S,4R,5R)-5- (6-amino-9H-purin-9-yl)-4-hydroxy- 3-(phosphonooxy)tetrahydrofuran-2-yl]- 3,5,9,21-tetrahydroxy-8,8,21-trimethyl- 10,14,19-trioxo-2,4,6-trioxa-18-thia- 11,15-diaza-3,5-diphosphatricosan-23- oic acid 3,5-dioxide
Identifiers
CAS number	1553-55-5
PubChem	84
MeSH	HMG-CoA
Properties
Molecular formula	C27H44N7O20P3S
Molar mass	911.661 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

HMG-CoA (or 3-hydroxy-3-methylglutaryl-coenzyme A) is an intermediate in the Mevalonate pathway. It is formed from acetyl CoA and acetoacetyl CoA by HMG-CoA synthase.

HMG-CoA reductase converts it into mevalonic acid.

Mevalonate pathway

Also, HMG-CoA lyase breaks it into acetyl CoA and acetoacetate.

Ketogenesis

It is also an intermediate in the metabolism of leucine. Its immediate precursor is 3-methylglutaconyl CoA.

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