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Gold Bond medicated powder is a brand of over-the-counter skin irritation medication produced by Chattem of Chattanooga, Tennessee. It is available as both a powder and a topical cream. Gold Bond is used to curb moisture, control odor, and soothe minor skin irritation, notably jock itch. Spin-off products are designed for specific uses, such as foot powders or powders for infants to treat diaper rash.

The active ingredients of Original Strength Gold Bond Powder are Menthol (0.15%) and zinc oxide (1.0%). Some product variants, such as Gold Bond Extra Strength Powder, offer higher concentrations of the active ingredients.

The powder is often referred to by Late Late Show host Craig Ferguson, who often peppers his monologues with the line, "It's the greatest invention since Gold Bond Medicated Powder."

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