Glucose 1-phosphate
Identifiers
CAS number	59-56-3 Y
PubChem	65533
MeSH	glucose-1-phosphate
Properties
Molecular formula	C6H13O9P
Molar mass	260.136
Y (what is this?)  (verify) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Glucose 1-phosphate (also called cori ester) is a glucose molecule with a phosphate group on the 1'-carbon.

Contents 1 Reactions 1.1 Catabolic 1.2 Anabolic 2 See also

[edit] Reactions

[edit] Catabolic

In glycogenolysis, it is the direct product of the reaction in which glycogen phosphorylase cleaves off a molecule of glucose from a greater glycogen structure.

To be utilized in cellular catabolism it must first be converted to glucose 6-phosphate by the enzyme phosphoglucomutase. One reason that cells form glucose 1-phosphate instead of glucose during glycogen breakdown is that the very polar phosphorylated glucose cannot leave the cell membrane and so is marked for intracellular catabolism.

[edit] Anabolic

In glycogenesis, free glucose 1-phosphate can also react with UTP to form UDP-glucose, by using the enzyme UDP-glucose pyrophosphorylase. It can then return to the greater glycogen structure via glycogen synthase.

[edit] See also

• Pentose phosphate pathway

This biochemistry article is a stub. You can help Wikipedia by expanding it. v • d • e

v • d • e Glycogenesis and glycogenolysis metabolic intermediates Glucose Glucose 6-phosphate · Glucose 1-phosphate Uridine Uridine diphosphate glucose · Uridine triphosphate Other Glycogen · Limit dextran see also enzymes, disorders

v • d • e Fructose and galactose metabolic intermediates Fructose Fructose-1-phosphate → DHAP/Glyceraldehyde → Glyceraldehyde 3-phosphate Galactose Galactose-1-phosphate → Glucose 1-phosphate → Glucose 6-phosphate → Fructose 6-phosphate Uridine diphosphate galactose · Uridine diphosphate glucose Galactitol · Iditol Mannose Mannose-6-phosphate → Fructose 6-phosphate see also enzymes, disorders