Gare de Lyon may refer to one of several railway stations in France:

• Gare de Lyon-Part-Dieu, the main railway station in the 3rd arrondissement of Lyon
• Gare de Lyon-Perrache, a railway station in the 2nd arrondissement of Lyon
• Gare de Lyon Saint-Exupéry, a railway station near Lyon, France, directly attached to Lyon-Saint Exupéry Airport
• Gare de Lyon-Gorge-de-Loup
• Gare de Lyon-Jean Macé
• Gare de Lyon-Saint-Paul
• Gare de Lyon-Vaise
• Gare des Brotteaux
• Gare de Lyon-Saint-Clair
• Gare de Lyon-Est
• Paris-Gare de Lyon, a railway station in the 12th arrondissement of Paris

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