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The "Gang of 22" was a group of Fianna Fáil Teachtaí Dála (members of parliament) who were opposed to the leadership of Charles Haughey in the early 1980s. The very evident division within the Fianna Fáil parliamentary party left a deep split in the organisation.

The origins of 'The Gang of 22' was when Desmond O'Malley challenged Charles Haughey for the leadership of Fianna Fáil in 1983. A vote of no-confidence Charles Haughey's leadership was called by Charlie McCreevy, and failed by 55 votes to 22. The Gang of 22 included Mary Harney, David Andrews, Séamus Brennan and Willie O'Dea.

The name is a pun on the Gang of Four, a group of Communist leaders in the People's Republic of China who were imprisoned after the death of Mao Zedong.