In anatomy, the G cell is a type of cell in the stomach that secretes gastrin. It works in conjunction with gastric chief cells and parietal cells.

G cells are found deep within the gastric glands of the stomach antrum, and occasionally in the pancreas.^[1]

The vagus nerve innervates the G cells.

Gastrin-releasing peptide is released by the post-ganglionic fibers of the vagus nerve onto G cells during parasympathetic stimulation.

Gastrin-releasing peptide, as well as the presence of amino acids in the stomach, stimulate the release of gastrin from the G cells. Gastrin stimulates enterochromaffin-like cells to release histamine.^[2]

Gastrin also targets parietal cells by increasing the amount of histamine and the direct stimulation by gastrin, causing the parietal cells to increase HCl secretion in the stomach.

[edit] References

1. ^ iv_1/g/G_cell article at GE's Medcyclopaedia
2. ^ Guyton, Arthur C.; John E. Hall (2006). Textbook of Medical Physiology (11 ed.). Philadelphia: Elsevier Saunders. p. 797. ISBN 0721602401. 

tt cells

[edit] External links

• Definition at thefreedictionary.com
• Physiology at MCG 6/6ch4/s6ch4_14

v • d • e Digestive system, physiology: gastrointestinal physiology GI tract Upper GI Exocrine Chief cells (Pepsinogen) · Parietal cells (Gastric acid, Intrinsic factor) · Goblet cells (Mucus) Processes Swallowing · Vomiting Fluids Saliva · Gastric juice Lower GI Enteric nervous system Meissner's plexus · Auerbach's plexus Endocrine/paracrine G cells (gastrin) · D cells (somatostatin) · ECL cells (Histamine) enterogastrone: I cells (CCK) · K cells (GIP) · S cells (secretin) Enteroendocrine cells · Enterochromaffin cell · APUD cell Border Brunner's glands · Paneth cells · Enterocytes Fluids Intestinal juice Processes Segmentation contractions · Migrating motor complex · Borborygmus · Defecation Either/both Processes Peristalsis (Interstitial cell of Cajal) · Gastrocolic reflex · Digestion Accessory Fluids Bile · Pancreatic juice Processes Enterohepatic circulation Abdominopelvic Peritoneal fluid digestive system navs: anat of tract,glands,perit,diaphragm/physio/dev, noncongen/congen/congen of d+w/neoplasia, symptoms+signs/eponymous, proc

v • d • e Human cell types Blood/immune lymphoid: B cell  · T cell (Cytotoxic T cell, Natural Killer T cell, Regulatory T cell, T helper cell) · Natural killer cell myeloid: granulocytes (Basophil granulocyte, Eosinophil granulocyte, Neutrophil granulocyte/Hypersegmented neutrophil)  · Monocyte/Macrophage  · Red blood cell (Reticulocyte)  · Mast cell  · Thrombocyte/Megakaryocyte  · Dendritic cell Endocrine system thyroid (Thyroid epithelial cell, Parafollicular cell)  · parathyroid (Parathyroid chief cell, Oxyphil cell)  · adrenal (Chromaffin cell) · pineal (Pinealocyte) Nervous system glial cells: Glioblast (Astrocyte, Oligodendrocyte) · Microglia Magnocellular neurosecretory cell  · Stellate cell · Boettcher cell pituitary (Gonadotrope, Corticotrope, Thyrotrope, Somatotrope, Lactotroph ) Respiratory system Pneumocyte (Type I pneumocyte, Type II pneumocyte) · Clara cell · Goblet cell · Alveolar macrophage Circulatory system Myocardiocyte · Pericyte Digestive system stomach (Gastric chief cell, Parietal cell) · Goblet cell · Paneth cell G cells · D cells · ECL cells · I cells  · K cells  · S cells Enteroendocrine cells · Enterochromaffin cell · APUD cell liver (Hepatocyte, Kupffer cell) Cartilage/bone/ muscle/ integumentary system bone: Osteoblast · Osteocyte · Osteoclast · teeth (Cementoblast, Ameloblast) cartilage: Chondroblast · Chondrocyte skin/hair: Trichocyte · Keratinocyte  · Melanocyte (Nevus cell) muscle: Myocyte other: Adipocyte  · Fibroblast (corneal keratocyte) · Tendon cell Urinary system Podocyte  · Juxtaglomerular cell  · Intraglomerular mesangial cell/Extraglomerular mesangial cell  · Kidney proximal tubule brush border cell  · Macula densa cell Reproductive system male (Spermatozoon, Sertoli cell, Leydig cell)  · female (Ovum) see also list of distinct cell types in the adult human body  · -cyte

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