Gamma-aminobutyric acid (GABA) A receptor, gamma 1, also known as GABRG1, is a human gene.[1] The protein encoded by this gene is a subunit of the GABAA receptor.[2] Variants of this gene may be associated with alcohol dependence.[3] [edit] References - ^ Wilcox AS, Warrington JA, Gardiner K, Berger R, Whiting P, Altherr MR, Wasmuth JJ, Patterson D, Sikela JM (July 1992). "Human chromosomal localization of genes encoding the gamma 1 and gamma 2 subunits of the gamma-aminobutyric acid receptor indicates that members of this gene family are often clustered in the genome". Proc. Natl. Acad. Sci. U.S.A. 89 (13): 5857–61. doi:10.1073/pnas.89.13.5857. PMID 1321425.
- ^ Hevers W, Lüddens H (August 1998). "The diversity of GABAA receptors. Pharmacological and electrophysiological properties of GABAA channel subtypes". Mol. Neurobiol. 18 (1): 35–86. doi:10.1007/BF02741459. PMID 9824848.
- ^ Ittiwut C, Listman J, Mutirangura A, Malison R, Covault J, Kranzler HR, Sughondhabirom A, Thavichachart N, Gelernter J (January 2008). "Interpopulation linkage disequilibrium patterns of GABRA2 and GABRG1 genes at the GABA cluster locus on human chromosome 4". Genomics 91 (1): 61–9. doi:10.1016/j.ygeno.2007.08.007. PMID 17976953.
[edit] External links | Ion channel, receptor: ligand-gated ion channels | | | Cys-loop receptors | | | | | | | GABAA ( α1, α2, α3, α4, α5, α6, β1, β2, β3, γ1, γ2, γ3, δ, ε, π, θ) · GABAA-ρ ( ρ1, ρ2, ρ3) | | | | | | | | | | | Zinc | | | | | Ionotropic glutamates | | Ligand-gated only | | | | Voltage- and ligand-gated | | | | | ATP-gated channels | | | |