Frontonasal prominence
Under surface of the head of a human embryo about twenty-nine days old. (Frontonasal process labeled at center left.)
Gray's	subject #13 67

During the third week two areas of thickened ectoderm, the olfactory areas, appear immediately under the fore-brain in the anterior wall of the stomodeum, one on either side of a region termed the frontonasal prominence (or process).

By the upgrowth of the surrounding parts these areas are converted into pits, the olfactory pits, which indent the frontonasal prominence and divide it into a medial and two lateral nasal processes.

There is some evidence that development involves Sonic hedgehog and Fibroblast growth factor 8.^[1]

[edit] References

[edit] External links

• hednk-027 — Embryology at UNC
• Flash animation at indiana.edu
• ent/30 at eMedicine

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v • d • e Human development of head and neck / branchial apparatus (GA 1.65) Nose Nasal placode · Olfactory pit · nasal prominences (Lateral, Medial) · Intermaxillary segment Mouth/neck Palate Primitive palate · Secondary palate 1st arch Frontonasal prominence · Maxillary prominence · Mandibular prominence (Meckel's cartilage) Anterior tongue: Lateral lingual swelling · Tuberculum impar Thyroid (pouches 3-5) Thyroid diverticulum · Thyroglossal duct · Ultimobranchial body General Pharyngeal groove (Cervical sinus) · Pharyngeal arch (1st, 2nd) · Pharyngeal pouch (Ultimobranchial body) respiratory system navs: anat nose,larynx/lower+thoracic cavity/physio/dev, noncongen/congen/tumors, symptoms+signs/eponymous, proc mouth navs: anat/dev, noncongen/congen face/congen GI/neoplasia, symptoms, proc endocrine navs: anat/physio/dev/hormones, noncongen/congen/neoplasia, symptoms+signs/eponymous, proc