Face Off may refer to the following:
- Faceoff, the ice hockey event that puts a puck into play
- Face/Off, the 1997 movie directed by John Woo and starring John Travolta and Nicolas Cage
- Invertigo (roller coaster), a roller coaster formerly known as Face/Off at Kings Island near Cincinnati, Ohio
- Face Off (arcade game), a Japan-only 1988 arcade game by Namco
- Face Off (FIRST), the 2008 FIRST Tech Challenge
- Face Off!, a 1987 ice hockey game by GameStar
- Face Off (Bow Wow & Omarion album), a collaboration album starring Bow Wow and Omarion
- Face Off (Pastor Troy album) by And ATL Rapper, Pastor Troy
- Face-Off?, a 1999 game show by Johnny "Hammond" Smith
- "Face-Off" (Gilmore Girls), a third-season episode of the television series Gilmore Girls
