FD can mean: - Canon FD lens mount
- Familial dysautonomia (HSAN Type III), also known as Riley-Day syndrome
- FD in a LARP game means "final death", or the end of one's character
- FD is the IATA code for Thai AirAsia
- FD is the model designation for the third generation of the Mazda RX-7
- McDonnell FD Phantom, pre-production designation for a United States Navy jet fighter later redesignated as the FH Phantom
- ferredoxin, a molecule functioning in electron transfer
- Fidei defensor ("Defender of the faith")
- file descriptor in the Unix operating system
- Final Destination (series), a horror film franchise focusing on teenagers cheating death
- Fire department, as in FDNY
- Flight director (aviation)
- Floppy disk
- Flashdrive
- Flying Dutchman (dinghy)
- Fort Davis
- Fortified District, a defensive fortified organization of the Imperial Japanese Army (World War II)
- Foundation Degree
- Free dance, the third part of an ice dancing competition
- Frisky Dingo, an animated show on Adult Swim
- full duplex on a network switch
- Functional dependency in a relation from a database
- Funeral director, a professional involved in the business of funeral rites
- St. John's Fog Devils, a QMJHL team based in St. John's
- Steam locomotive FD, Soviet steam locomotive
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