Epididymis Information & Epididymis Links at HealthHaven.com

Epididymis
	1: Epididymis; 2: Head of epididymis; 3: Lobules of epididymis; 4: Body of epididymis; 5: Tail of epididymis; 6: Duct of epididymis; 7: Deferent duct (ductus deferens or vas deferens)
	The right testis, exposed by laying open the tunica vaginalis.
Gray's	subject #258 1242
Vein	Pampiniform plexus
Precursor	Wolffian duct
MeSH	Epididymis

The epididymis (pronounced /ɛpɨˈdɪdɨmɪs/, plural: epididymides /ɛpɨˌdɪdɨˈmiːdiːz/) is part of the male reproductive system and is present in all male amniotes. It is a narrow, tightly-coiled tube connecting the efferent ducts from the rear of each testicle to its vas deferens. A similar, but probably non-homologous, structure is found in cartilaginous fishes.

[edit] Regions

The epididymis can be divided into three main regions

The head (Caput). The head of the epididymis receives spermatozoa via the efferent ducts of the mediastinum of the testis. It is characterized histologically by a thin myoepithelium. The concentration of the sperm here is dilute.
The body (Corpus)
The tail (Cauda). This has a thicker myoepithelium than the head region, as it is involved in absorbing fluid to make the sperm more concentrated.

In reptiles, there is an additional canal between the testis and the head of the epididymis, which receives the various efferent ducts. This is, however, absent in all birds and mammals.^[1]

[edit] Role in storage of sperm and ejaculation

Spermatozoa formed in the testis enter the caput epididymis, progress to the corpus, and finally reach the cauda region, where they are stored. Sperm entering the caput epididymis are incomplete - they lack the ability to swim forward (motility) and to fertilize an egg. During their transit in the epididymis, sperm undergo maturation processes necessary for them to acquire these functions.^[2] Final maturation is completed in the female reproductive tract (capacitation).

During ejaculation, sperm flow from the lower portion of the epididymis (which functions as a storage reservoir). They have not been activated by products from the prostate gland, and they are unable to swim, but are transported via the peristaltic action of muscle layers within the vas deferens, and are mixed with the diluting fluids of the seminal vesicles and other accessory glands prior to ejaculation (forming semen).

The epididymis possesses numerous, long atypical microvilli. These processes are often called stereocillia; this is incorrect, as they neither contain the microtubular structures of cilia nor function like cilia.^[3]

[edit] Pathology

An inflammation of the epididymis is called epididymitis.

[edit] Embryology and vestigial structures

A Gartner's duct is a homologous remnant in the female.

In the embryo, the epididymis develops from tissue that once formed the mesonephros, a primitive kidney found in many aquatic vertebrates. Persistence of the cranial end of the mesonephric duct will leave behind a remnant called the appendix of the epididymis. In addition, some mesonephric tubules can persist as the paradidymis, a small body caudal to the efferent ductules.

[edit] Epididymectomy

This is the surgical removal of the Epididymis carried out under local anaesthesia. This is most often performed to relieve pain associated post-Vasectomy.

[edit] Gallery

Male reproductive system.

Testis

Schematic drawing of a cross-section through a testicle.

Microscopic shot.

[edit] Notes

^ Romer, Alfred Sherwood; Parsons, Thomas S. (1977). The Vertebrate Body. Philadelphia, PA: Holt-Saunders International. pp. 394-395. ISBN 0-03-910284-X.
^ Jones R (1999). "To store or mature spermatozoa? The primary role of the epididymis". Int J Androl 22 (2): 57–67. doi:10.1046/j.1365-2605.1999.00151.x. PMID 10194636. abstract
^ Stevens, Alan; Lowe, James N. (2005). Human histology. Philadelphia: Elsevier Mosby. ISBN 978-0-323-03663-4.

[edit] External links

Histology at BU 16903loa
inguinalregion at The Anatomy Lesson by Wesley Norman (Georgetown University) (testes)

[VB-0] Romer, Alfred Sherwood; Parsons, Thomas S. (1977). The Vertebrate Body. Philadelphia, PA: Holt-Saunders International. pp. 394-395. ISBN 0-03-910284-X.

[1] Jones R (1999). "To store or mature spermatozoa? The primary role of the epididymis". Int J Androl 22 (2): 57–67. doi:10.1046/j.1365-2605.1999.00151.x. PMID 10194636. abstract

[2] Stevens, Alan; Lowe, James N. (2005). Human histology. Philadelphia: Elsevier Mosby. ISBN 978-0-323-03663-4.

[1]

[2]

[3]

Contents