EMR1 Information & EMR1 Links at HealthHaven.com

Egf-like module containing, mucin-like, hormone receptor-like 1
Identifiers
Symbols	EMR1; TM7LN3
External IDs	OMIM: 600493 MGI: 106912 HomoloGene: 1493 IUPHAR: EMR1 GeneCards: EMR1 Gene
Gene ontology
Molecular function	• receptor activity; • G-protein coupled receptor activity; • calcium ion binding;
Cellular component	• integral to plasma membrane; • membrane; • integral to membrane;
Biological process	• cell adhesion; • signal transduction; • neuropeptide signaling pathway;
RNA expression pattern
	More reference expression data
Orthologs

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EGF-like module-containing mucin-like hormone receptor-like 1 is a protein that in humans is encoded by the EMR1 gene.^[1]^[2]^[3]

This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties.^[3]

[edit] See also

EGF module-containing mucin-like hormone receptor

[edit] References

^ Baud V, Chissoe SL, Viegas-Pequignot E, Diriong S, N'Guyen VC, Roe BA, Lipinski M (Aug 1995). "EMR1, an unusual member in the family of hormone receptors with seven transmembrane segments". Genomics 26 (2): 334-44. PMID 7601460.
^ McKnight AJ, Gordon S (Mar 1998). "The EGF-TM7 family: unusual structures at the leukocyte surface". J Leukoc Biol 63 (3): 271-80. PMID 9500513.
^ ^a ^b "Entrez Gene: EMR1 egf-like module containing, mucin-like, hormone receptor-like 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2015.

[edit] Further reading

McKnight AJ, Macfarlane AJ, Seldin MF, Gordon S (1998). "Chromosome mapping of the Emr1 gene.". Mamm. Genome 8 (12): 946. doi:10.1007/s003359900633. PMID 9383301.
Carver EA, Hamann J, Olsen AS, Stubbs L (2000). "Physical mapping of EMR1 and CD97 in human Chromosome 19 and assignment of Cd97 to mouse Chromosome 8 suggest an ancient genomic duplication.". Mamm. Genome 10 (10): 1039–40. doi:10.1007/s003359901157. PMID 10501980.
Lin HH, Stacey M, Hamann J, et al. (2000). "Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97.". Genomics 67 (2): 188–200. doi:10.1006/geno.2000.6238. PMID 10903844.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

[pmid7601460-0] Baud V, Chissoe SL, Viegas-Pequignot E, Diriong S, N'Guyen VC, Roe BA, Lipinski M (Aug 1995). "EMR1, an unusual member in the family of hormone receptors with seven transmembrane segments". Genomics 26 (2): 334-44. PMID 7601460.

[pmid9500513-1] McKnight AJ, Gordon S (Mar 1998). "The EGF-TM7 family: unusual structures at the leukocyte surface". J Leukoc Biol 63 (3): 271-80. PMID 9500513.

[entrez-2] "Entrez Gene: EMR1 egf-like module containing, mucin-like, hormone receptor-like 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2015.

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