Dystrophin-associated protein complex Information & Dystrophin-associated protein complex Links at HealthHaven.com

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The dystrophin-associated protein complex is a multiprotein complex that includes dystrophin and the dystrophin-associated proteins.^[1]

Many forms of muscular dystrophy are associated with disorders of the dystrophin-associated protein complex.^[2]

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Costamere/
DAPC

Membrane/ extracellular	DAP: Sarcoglycan (SGCA, SGCB, SGCD, SGCE, SGCG, SGCZ) · Dystroglycan Sarcospan · Laminin, alpha 2

Intracellular	Dystrophin · Dystrobrevin (A, B) · Syntrophin (A, B1, B2, G1, G2) · Syncoilin · Dysbindin · Synemin/desmuslin related: NOS1 · Caveolin 3

General

General

Connective tissue	Epimysium · Fascicle · Perimysium · Endomysium

Fiber	Muscle fiber (intrafusal, extrafusal) · Myofibril · Microfilament/Myofilament

Sarcomere/ (a, i, and h bands; z and m lines)	Myofilament (thin filament/actin, thick filament/myosin, elastic filament/titin, nebulin) Tropomyosin Troponin (T, C, I)

Cells	Myoblast/Myocyte · Satellite cell

Other	Desmin · Sarcoplasm · Sarcolemma (T-tubule) · Sarcoplasmic reticulum

Other/
ungrouped

muscle, DF+DRCT navs: anat/hist/physio, acquired myopathy/congenital myopathy/neoplasia, symptoms+signs/eponymous, proc