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Inositol Pyrophosphates -Echelon Biosciences Inc. echelon-inc.com | Pseudogout and Calcium Pyrophosphate Deposition Disease - New... ccspublishing.com | Pseudogout and Calcium Pyrophosphate Deposition Disease - New... medical-library.org | Calcium pyrophosphate deposition disease (Chondrocalcinosis, Pseudogout) virtualbonecentre.com |
Dimethylallyl pyrophosphate (or -diphosphate) (DMAPP) is an intermediate product of both mevalonic acid (MVA) pathway and DOXP/MEP pathway. It is an isomer of isopentenyl pyrophosphate (IPP) and exists in virtually all life forms. Precursor of DMAPP in the MVA pathway is mevalonic acid, and 2-C-methyl-D-erythritol-e-P in the MEP/DOXP pathway. At present, it is believed that there is crossover between the two pathways in organisms that use both pathways to create terpenes and terpenoids, such as in plants, and that DMAPP is the crossover product. Simplified version of the steroid synthesis pathway with the intermediates isopentenyl pyrophosphate (IPP), dimethylallyl pyrophosphate (DMAPP), geranyl pyrophosphate (GPP) and squalene shown. Some intermediates are omitted. [edit] External links
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