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Dihydrofolic acid

Identifiers
CAS number	4033-27-6
PubChem	661
MeSH	dihydrofolate
Properties
Molecular formula	C₁₉H₂₁N₇O₆
Molar mass	443.414 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Dihydrofolic acid is a folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid. It interacts with bacteria during cell division. It is targeted by various drugs to prevent nucleic acid synthesis. Dihydrofolic acid is also known by the name Dihydrofolate - more commonly Vitamin B9.

v • d • e Enzyme cofactors

Active Forms	vitamins: TPP / ThDP (B₁) · FMN, FAD (B₂) · NAD⁺, NADH, NADP⁺, NADPH (B₃) · Coenzyme A (B₅) · PLP / P5P (B₆) · Biotin (B₇) · THFA / H₄FA, DHFA / H₂FA, MTHF (B₉) · AdoCbl, MeCbl (B₁₂) · Ascorbic Acid (C) · Phylloquinone (K₁, Menaquinone (K₂) · Coenzyme F420 non-vitamins: ATP · CTP · SAMe · PAPS · GSH · Coenzyme B · Coenzyme M · Coenzyme Q · Heme / Haem (A, B, C, O) · Lipoic Acid · Methanofuran · Molybdopterin · PQQ · THB / BH₄ · THMPT / H₄MPT minerals: Ca²⁺ · Cu²⁺ · Fe²⁺, Fe³⁺ · Mg²⁺ · Mn²⁺ · Mo · Ni²⁺ · Se · Zn²⁺

Base Forms	vitamins: Thiamine (B₁) · Riboflavin (B₂) · Niacin, Niacinamide (B₃) · Pantothenic Acid (B₅) · Pyridoxine, Pyridoxamine, Pyridoxal (B₆) · Cyanocobalamin, Hydroxocobalamin (B₁₂)

Major families of biochemicals Saccharides/Carbohydrates/Glycosides · Amino acids/Peptides/Proteins/Glycoproteins · Lipids/Terpenes/Steroids/Carotenoids · Alkaloids/Nucleobases/Nucleic acids · Cofactors/Phenylpropanoids/Polyketides/Tetrapyrroles

A	Retinol · β-Carotene · Tretinoin · α-Carotene

D	D₂ (Ergosterol, Ergocalciferol) · D₃ (7-Dehydrocholesterol, Previtamin D3, Cholecalciferol, 25-hydroxycholecalciferol, Calcitriol (1,25-dihydroxycholecalciferol), Calcitroic acid) D₄ (Dihydroergocalciferol) · D₅ · D analogues (Dihydrotachysterol, Calcipotriol, Tacalcitol, Paricalcitol)

E	Tocopherol (Alpha, Beta, Gamma, Delta) · Tocotrienol · Tocofersolan

K	Naphthoquinone · Phylloquinone/K1 · Menatetrenone/K2 · Menadione/K3

B	B₁ (Thiamine) · B₂ (Riboflavin) · B₃ (Niacin, Nicotinamide) · B₅ (Pantothenic acid, Dexpanthenol, Pantethine) · B₆ (Pyridoxine, Pyridoxal phosphate, Pyridoxamine) B₇ (Biotin) · B₉ (Folic acid, Dihydrofolic acid, Folinic acid) · B₁₂ (Cyanocobalamin, Hydroxocobalamin, Methylcobalamin, Cobamamide) · Choline

C	Ascorbic acid · Dehydroascorbic acid

see also: enzyme cofactors, enzymes, Multivitamins

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