Cryptoxanthin Information & Cryptoxanthin Links at HealthHaven.com

Cryptoxanthin
IUPAC name	(R)-3,5,5-Trimethyl-4-[3,7,12,16-; tetramethyl-18-(2,6,6-trimethylcyclohex-; 1-enyl)-octadeca-1,3,5,7,9,11,13,15,17-; nonaenyl]-cyclohex-3-enol
Other names	(3R)-β,β-Caroten-3-ol; Cryptoxanthol; Caricaxanthin; (R)-all-trans-β-Caroten-3-ol; Hydroxy-β-carotene
Identifiers
CAS number	472-70-8
SMILES	CC1(C)C[C@@H](O)CC(C)=C1/C=C/C; (C)=C/C=C/C(C)=C/C=C/C=C(C)/C; =C/C=C(C)/C=C/C2=C(C)CCCC(C)2C
Properties
Molecular formula	C40H56O
Molar mass	552.85 g/mol
Density	? g/cm3
Melting point	169 °C
	(what is this?) (verify); Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
	Infobox references

Cryptoxanthin is a natural carotenoid pigment. It has been isolated from a variety of sources including the petals and flowers of plants in the genus Physalis, orange rind, papaya, egg yolk, butter, apples, and bovine blood serum.^[1]

[edit] Chemistry

In terms of structure, cryptoxanthin is closely related to beta-carotene, with only the addition of a hydroxyl group. It is a member of the class of carotenoids known as xanthophylls.

In a pure form, cryptoxanthin is a red crystalline solid with a metallic luster. It is freely soluble in chloroform, benzene, pyridine, and carbon disulfide.^[1]

[edit] Biology and medicine

In the human body, cryptoxanthin is converted to vitamin A (retinol) and is, therefore, considered a provitamin A. As with other carotenoids, cryptoxanthin is an antioxidant and may help prevent free radical damage to cells and DNA, as well as stimulate the repair of oxidative damage to DNA. ^[2]

Recent findings of an inverse association between β-cryptoxanthin and lung cancer risk in several observational epidemiological studies suggest that β-cryptoxanthin could potentially act as a chemopreventive agent against lung cancer.^[3]

[edit] References

^ ^a ^b ^c Merck Index, 11th Edition, 2612.
^ http://carcin.oxfordjournals.org/cgi/content/short/30/2/308
^ β-Cryptoxanthin suppresses the growth of immortalized human bronchial epithelial cells and non-small-cell lung cancer cells and up-regulates retinoic acid receptor b expression. Lian, Fuzhi; Hu, Kang-Quan; Russell, Robert M.; Wang, Xiang-Dong. International Journal of Cancer (2006), 119(9), 2084-2089.

[Merck-0] Merck Index, 11th Edition, 2612.

[1] ttp://carcin.oxfordjournals.org/cgi/content/short/30/2/308

[2] β-Cryptoxanthin suppresses the growth of immortalized human bronchial epithelial cells and non-small-cell lung cancer cells and up-regulates retinoic acid receptor b expression. Lian, Fuzhi; Hu, Kang-Quan; Russell, Robert M.; Wang, Xiang-Dong. International Journal of Cancer (2006), 119(9), 2084-2089.

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