Chromonychia Information & Chromonychia Links at HealthHaven.com

Chromonychia is a term used to indicate an abnormality in color of the substance and/or surface of the nail plate and/or subungual tissues.^[1]^:658

Chromonychia can be induced by antineoplastic drugs with few distinct forms, the most frequently seen is melanonychia.^[2]. Although a few cytostatics may cause these changes, the drugs most commonly involved are adriamycin, cyclophosphamide and vincristine, or in polychemotherapy^[3]^[4]

Also chromonychia is associated with AIDS. A significant association (p<0.05) was found between chromonychia and CD4 counts of below 200 per cubic millimeter^[5].

[edit] References

^ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0071380760.
^ Unamuno P, Fernández-López E, Santos C (July 1992). "Leukonychia due to cytostatic agents". Clin. Exp. Dermatol. 17 (4): 273–4. PMID 1451320.
^ Chapman S, Cohen PR (April 1997). "Transverse leukonychia in patients receiving cancer chemotherapy". South. Med. J. 90 (4): 395–8. PMID 9114829. http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0038-4348&volume=90&issue=4&spage=395.
^ Dasanu, Constantin A (October 31, 2006). "Distinct patterns of chromonychia, Beau's lines, and melanoderma seen with vincristine, adriamycin, dexamethasone therapy for multiple myeloma". Dermatology Online Journal 12 (6): 10. http://dermatology.cdlib.org/126/case_reports/nail/dasanu.html.
^ Monsel G, Ly F, Canestri A, Diousse P, Ndiaye B, Caumes E (March 2008). "[Prevalence of skin disorders in HIV patients in Senegal and relationship to degree of immunosuppression]" (in French). Ann Dermatol Venereol 135 (3): 187–93. doi:10.1016/j.annder.2007.11.022. PMID 18374849.

This dermatology article is a stub. You can help Wikipedia by expanding it.

[Fitz2-0] Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0071380760.

[pmid1451320-1] Unamuno P, Fernández-López E, Santos C (July 1992). "Leukonychia due to cytostatic agents". Clin. Exp. Dermatol. 17 (4): 273–4. PMID 1451320.

[pmid9114829-2] Chapman S, Cohen PR (April 1997). "Transverse leukonychia in patients receiving cancer chemotherapy". South. Med. J. 90 (4): 395–8. PMID 9114829. http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0038-4348&volume=90&issue=4&spage=395.

[3] Dasanu, Constantin A (October 31, 2006). "Distinct patterns of chromonychia, Beau's lines, and melanoderma seen with vincristine, adriamycin, dexamethasone therapy for multiple myeloma". Dermatology Online Journal 12 (6): 10. http://dermatology.cdlib.org/126/case_reports/nail/dasanu.html.

[pmid18374849-4] Monsel G, Ly F, Canestri A, Diousse P, Ndiaye B, Caumes E (March 2008). "[Prevalence of skin disorders in HIV patients in Senegal and relationship to degree of immunosuppression]" (in French). Ann Dermatol Venereol 135 (3): 187–93. doi:10.1016/j.annder.2007.11.022. PMID 18374849.

[1]

[2]

[3]

[4]

[5]