ChemMedChem is a monthly peer-reviewed medicinal chemistry journal. It is co-owned by the 14 European chemical society members of ChemPubSoc Europe and is published by Wiley-VCH. Its 2008 impact factor is 3.150, and its immediacy index is 0.645.[1] In addition to original research in the form of full papers and shorter communications, ChemMedChem contains review-type articles (reviews, minireviews, essays, highlights) as well as occasional book reviews and conference reports. The first volume was published at the beginning of 2006 under the two founding chemical societies, the German Chemical Society (GDCh) and the Italian Chemical Society (SCI). Since then, 12 additional chemical societies have joined in co-ownership of the journal. ChemMedChem is a sister publication to other scientific journals published by Wiley-VCH, including Angewandte Chemie, ChemBioChem, ChemPhysChem, ChemSusChem, and ChemCatChem. Topics covered in ChemMedChem include drug design, development and delivery, molecular modeling, combinatorial chemistry, drug target validation, lead generation, and ADMET studies. [edit] Most highly cited papers as of August 2009 Last update 11.08.2009:[1] - Jean-Michel Rondeau, Francis Bitsch, Emmanuelle Bourgier, Martin Geiser, Rene Hemmig, Markus Kroemer, Sylvie Lehmann, Paul Ramage, Sebastien Rieffel, André Strauss, Jonathan R. Green, Wolfgang Jahnke, "Structural Basis for the Exceptional in vivo Efficacy of Bisphosphonate Drugs" (Full Paper), ChemMedChem 2006, 1, 267.
- Facundo M. Fernández, Robert B. Cody, Michael D. Green, Christina Y. Hampton, Rose McGready, Sivong Sengaloundeth, Nicholas J. White, Paul N. Newton, "Characterization of Solid Counterfeit Drug Samples by Desorption Electrospray Ionization and Direct-analysis-in-real-time Coupled to Time-of-flight Mass Spectrometry" (Communication), ChemMedChem 2006, 1, 702.
- Felix Kratz, Ivonne A. Müller, Claudia Ryppa, André Warnecke, "Prodrug Strategies in Anticancer Therapy" (Review), ChemMedChem 2008, 3, 20.
- Naoki Kanayama, Shigeto Fukushima, Nobuhiro Nishiyama, Keiji Itaka, Woo-Dong Jang, Kanjiro Miyata, Yuichi Yamasaki, Ung-il Chung, Kazunori Kataoka, "A PEG-Based Biocompatible Block Catiomer with High Buffering Capacity for the Construction of Polyplex Micelles Showing Efficient Gene Transfer toward Primary Cells" (Full Paper), ChemMedChem 2006, 1, 439.
- M. Novella Romanelli, Paola Gratteri, Luca Guandalini, Elisabetta Martini, Claudia Bonaccini, Fulvio Gualtieri, "Central Nicotinic Receptors: Structure, Function, Ligands, and Therapeutic Potential" (Review), ChemMedChem 2007, 2, 746.
- Karl-Heinz Altmann, Bernhard Pfeiffer, Stellios Arseniyadis, Benjamin A. Pratt, K.C. Nicolaou, "The Chemistry and Biology of Epothilones - The Wheel Keeps Turning" (Review), ChemMedChem 2007, 2, 396.
- Dieter Häbich, Franz von Nussbaum, "Platensimycin, a New Antibiotic and “Superbug Challenger” from Nature" (Highlight), ChemMedChem 2006, 1, 951.
- Angela Casini, Guido Mastrobuoni, Wee Han Ang, Chiara Gabbiani, Giuseppe Pieraccini, Gloriano Moneti, Paul J. Dyson, Luigi Messori, "ESI-MS Characterisation of Protein Adducts of Anticancer Ruthenium(II)-Arene PTA (RAPTA) Complexes" (Communication), ChemMedChem 2007, 2, 631.
- Steffen Renner, Gisbert Schneider, "Scaffold-Hopping Potential of Ligand-Based Similarity Concepts" (Communication), ChemMedChem 2006, 1, 181.
- D. Christopher Meadows, Jacquelyn Gervay-Hague, "Current Developments in HIV Chemotherapy" (Review), ChemMedChem 2006, 1, 16.
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