Casca could be:

• CASCA: The Canadian Astronomical Society
• CASCA: The Canadian Anthropological Society
• Servilius Casca, one of the assassins of Julius Caesar
• Casca Rufio Longinius, an immortal fictional soldier created by Barry Sadler
• Casca (series), a series of paperback novels about Casca Rufio Longinius
• Casca, Rio Grande do Sul, municipality of Brazil
• Casca District, in Peru
• Casca, a character in the anime and manga series Berserk

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