Carnitine O-palmitoyltransferase (also called carnitine palmitoyltransferase or carnitine acyltransferase) is a mitochondrial transferase enzyme (EC 2.3.1.21) involved in the metabolism of palmitoylcarnitine into palmitoyl-CoA.

[edit] Molecules

Palmitoylcarnitine

Palmitoyl CoA

[edit] Pathway

Acyl-CoA from cytosol to the mitochondrial matrix.gif

[edit] Human forms of CPT

There are four different forms of CPT in humans:

• CPT1A - associated with Carnitine palmitoyltransferase I deficiency
• CPT1B
• CPT1C
• CPT2 - associated with Carnitine palmitoyltransferase II deficiency

[edit] See also

• Fatty_acid_degradation#Transport_into_the_mitochondrial_matrix

[edit] External links

• PDOC00402 - Acyltransferases ChoActase / COT / CPT family in PROSITE
• Choline/Carnitine o-acyltransferase family in Pfam
• UMich Orientation of Proteins in Membranes protein/pdbid-2h4t
• MeSH Carnitine+O-Palmitoyltransferase