The cardiac neural crest is a form of neural crest.^[1]

The cardiac neural crest develops from the dorsal neural tube.^[2] It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart.

Other Migration Locations:

• Into the pharyngeal arches and Truncus arteriosus (embryology), forming the aorticopulmonary septum^[3] and the smooth muscle of great arteries.
• Anterior of the aorta to become the four pre-aortic ganglia (celiac ganglion, superior mesenteric ganglion, inferior mesenteric ganglion and aortical renal ganglia)

Notch2 plays an important role in development.^[4]

[edit] References

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v • d • e Prenatal development/Mammalian development of nervous system (GA 9.733) General neural development/ neurulation/neurula Notochord · Neuroectoderm · Neural plate · Neural folds · Neural groove Neural crest (Cranial, Trunk, Cardiac) · Neural tube (Neuromere/Rhombomere, Cephalic flexure) Alar plate (sensory) · Basal plate (motor) Glioblast · Neuroblast note: mostly ecoderm, but mesoderm is precursor for epineurium, perineurium, and endoneurium central nervous system navs: anat/physio/dev, noncongen/congen/neoplasia, symptoms+signs/eponymous, proc