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cytochrome P450, family 4, subfamily A, polypeptide 22
Identifiers
Symbol CYP4A22
Entrez 284541
HUGO 20575
RefSeq XM_208213
UniProt Q5TCH4
Other data
EC number 1.14.15.3
Locus Chr. 1 p33

CYP4A22 (cytochrome P450, family 4, subfamily A, polypeptide 22) also known as fatty acid omega-hydroxylase is a protein which in humans is encoded by the CYP4A22 gene.[1]

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33.[2]

[edit] References

  1. ^ Hiratsuka M, Nozawa H, Katsumoto Y, Moteki T, Sasaki T, Konno Y, Mizugaki M (July 2006). "Genetic polymorphisms and haplotype structures of the CYP4A22 gene in a Japanese population". Mutat. Res. 599 (1-2): 98–104. doi:10.1016/j.mrfmmm.2006.02.008. PMID 16806293. 
  2. ^ "Entrez Gene: CYP4A22". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=284541. 

This article incorporates text from the United States National Library of Medicine, which is in the public domain.





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