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CYP2U1
Identifiers
Symbol CYP2U1
Entrez 113612
HUGO 20582
OMIM 610670
RefSeq NM_183075
UniProt Q7Z449
Other data
Locus Chr. 4 q25

CYP2U1 (cytochrome P450, family 2, subfamily U, polypeptide 1) is a protein which in humans is encoded by the CYP2U1 gene[1]

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.[2] CYP2U1 metabolized arachidonic acid, docosahexaenoic acid (DHA), and other long chain fatty acids which suggests that CYP2U1 may play a role in brain and immune functions.[1]

[edit] References

  1. ^ a b Chuang SS, Helvig C, Taimi M, Ramshaw HA, Collop AH, Amad M, White JA, Petkovich M, Jones G, Korczak B (February 2004). "CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes omega- and (omega-1)-hydroxylation of fatty acids". J. Biol. Chem. 279 (8): 6305–14. doi:10.1074/jbc.M311830200. PMID 14660610. 
  2. ^ "Entrez Gene: CYP2U1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=113612. 

This article incorporates text from the United States National Library of Medicine, which is in the public domain.




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