CYP2B6 Information & CYP2B6 Links at HealthHaven.com

cytochrome P450, family 2, subfamily B, polypeptide 6
Identifiers
Symbol	CYP2B6
Entrez	1555
HUGO	2615
OMIM	123930
RefSeq	NM_000767
UniProt	P20813
Other data
Locus	Chr. 19 q13.2

CYP2B6 is a member of the Cytochrome P450 group of enzymes. Along with CYP2A6, it is involved with metabolizing nicotine, along with many other substances.

[edit] CYP2B6 Ligands

Substrates	Inhibitors	Inducers
Often mentioned ^[1]: Bupropion (antidepressant) Cyclophosphamide (Alkylating antineoplastic agent) Efavirenz (NNRTI) Ifosfamide (Alkylating antineoplastic agent) Selegiline (monoamine oxidase inhibitors) Other: Alfentanil (opioid analgesic) Nevirapine (NNRTI) Propofol (anesthetic) tamoxifen (SERM) Valproic acid (anticonvulsant , mood-stabilizing) Artemisinin (against malaria) Pethidine (analgesic) Nicotine (stimulant) Modafinil (stimulant-like) Sertraline (SSRI) thiotepa (Alkylating antineoplastic agent)	Strong ^[2]: Orphenadrine (analgesic) unspecified: Paroxetine (SSRI) fluoxetine (SSRI) Estradiol (sex hormone) Phencyclidine (dissociative) ritonavir (antiretroviral) sertraline (SSRI) thiotepa (Alkylating antineoplastic agent) ticlopidine (antiplatelet)	Often mentioned ^[1]: carbamazepine (anticonvulsant, mood stabilizer) rifampicin (bactericidal) Other: artemisinin (against malaria) clotrimazole (antifungal) ifosfamide (Alkylating antineoplastic agent) glucocorticoids (antiinflammatory) phenobarbital (anticonvulsant ) phenytoin (antiepileptic) ritonavir (antiretroviral)

[edit] References

^ ^a ^b Mentioned both in the reference named FASS and were previously mentioned in Wikipedia. Further contributions may follow other systems
^ Swedish environmental classification of pharmaceuticals Facts for prescribers (Fakta för förskrivare)

[edit] External links

MeSH CYP2B6

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[importance-0] Mentioned both in the reference named FASS and were previously mentioned in Wikipedia. Further contributions may follow other systems

[FASS-1] Swedish environmental classification of pharmaceuticals Facts for prescribers (Fakta för förskrivare)

[1]

[2]