CIE is an acronym which can stand for:
- Cleveland Institute of Electronics, a private technical and engineering educational institution
- Cambridge International Examinations, an international examination board
- Computability in Europe, an international organization of computability theorists, computer scientists, mathematicians
- Commercial Information Exchange, a real estate database for commercial properties, similar to a residential Multiple Listing Service (MLS)
- Christmas in Ethiopia, a support group for abandoned animals in Ethiopia
- French: Commission Internationale de l'Eclairage — the International Commission on Illumination
- French: Compagnie ivoirienne d'électricité, the national electrical company in Ivory Coast
- Companion of the Order of the Indian Empire (C.I.E.)
- the postnominal of a Companion of the Order of the Indian Empire
- Control and Indicating Equipment
- Córas Iompair Éireann, the Irish state transport authority
- Corpus Inscriptionum Etruscarum, the known body of Etruscan inscriptions
- Council on Islamic Education
- Counterimmunoelectrophoresis
- Transportes Aéreos Cielos Andinos, ICAO code CIE
“Cie” is an abbreviation for French: “Compagnie” (“Company”).