CGI may mean: - California Graduate Institute, an independent graduate school specializing in psychology
- Commission for the Management and Application of Geoscience Information, a Commission of the International Union of Geological Sciences to enable the global exchange of knowledge about geoscience information and systems
- Computer-generated imagery, computer graphic effects in films, television programs, and other visual media
- Common Gateway Interface, a protocol for calling external software via a web server to deliver dynamic content (and .cgi, its associated file extension)
- Compacted graphite iron, a type of cast iron
- CGI Group, an information technology and business process services company
- CGI.pm, a Perl module for implementing Common Gateway Interface programs
- Cape Girardeau Regional Airport, an airport (IATA airport code: CGI) in Cape Girardeau, Missouri, United States
- Catholic Guides of Ireland, a girl guide association
- Cell Global Identity, unique identifier of a cell site in cellular networks such as GSM and UMTS
- CpG islands, genomic regions that contain a high frequency of CG dinucleotides.
- Clinical Global Impression, a scale to assess treatment response associated with mental disorders
- Clinton Global Initiative, a forum created by former US President Bill Clinton to discuss global problems
- Coast Guard Intelligence, the intelligence branch of the United States Coast Guard
- Consultative Group on Indonesia, a former gathering of donors to the Indonesian government
- Corrugated galvanised iron, a type of molded sheet-metal
- Cuerpo Guardia de InfanterÃa, an Argentine police riot control service
- Cognitively Guided Instruction, an approach to mathematics teaching and learning that focuses on students' thinking and solution strategies
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