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Signaling pathway of TNF-R1. Dashed grey lines represent multiple steps
tumor necrosis factor receptor superfamily, member 1A
Identifiers
Symbol TNFRSF1A
Alt. symbols CD120a, TNFR1
Entrez 7132
HUGO 11916
OMIM 191190
RefSeq NM_001065
UniProt P19438
Other data
Locus Chr. 12 p13.2
tumor necrosis factor receptor superfamily, member 1B
Identifiers
Symbol TNFRSF1B
Alt. symbols CD120a, TNFR2
Entrez 7133
HUGO 11917
OMIM 191191
RefSeq NM_001066
UniProt P20333
Other data
Locus Chr. 1 p36.22

CD120 (Cluster of Differentiation 120), also known as the tumor necrosis factor receptor (TNFR). This protein is a member of the tumor necrosis factor receptor superfamily.[1][2]

Contents

[edit] Receptor subtypes

There are two variants of the receptor, each encoded by a separate gene:

[edit] See also

[edit] References

  1. ^ Locksley RM, Killeen N, Lenardo MJ (2001). "The TNF and TNF receptor superfamilies: integrating mammalian biology". Cell 104 (4): 487–501. doi:10.1016/S0092-8674(01)00237-9. PMID 11239407. 
  2. ^ Hehlgans T, Pfeffer K (2005). "The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games". Immunology 115 (1): 1–20. doi:10.1111/j.1365-2567.2005.02143.x. PMID 15819693. 

[edit] External links




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