This article does not cite any references or sources. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. (April 2008)

Brunner's glands
Section of duodenum. (Duodenal glands in submucosa labeled at right, fourth from the top.)
Latin	glandulae duodenales
Gray's	subject #248 1176

Brunner glands (or Pancreal glands or "duodenal glands") are compound tubular submucosal glands found in that portion of the duodenum which is above the sphincter of Oddi. The main function of these glands is to produce a mucus-rich alkaline secretion (containing bicarbonate) in order to:

• protect the duodenum from the acidic content of chyme (which is introduced into the duodenum from the stomach);
• provide an alkaline condition for the intestinal enzymes to be active, thus enabling absorption to take place;
• lubricate the intestinal walls.

They are the distinguishing feature of the duodenum, and are named for the Swiss physician who first described them, Johann Conrad Brunner.

[edit] External links

• duodenal+glands at eMedicine Dictionary
• Histology at BU 11504loa - "Digestive System: Alimentary Canal: pyloro/duodenal junction, duodenum"
• Histology at BU 11513loa - "Digestive System: Alimentary Canal: pyloro/duodenal junction"
• Histology at BU 11609loa - "Digestive System: Alimentary Canal: duodenum, plicae circularis"

v • d • e Digestive system, physiology: gastrointestinal physiology GI tract Upper GI Exocrine Chief cells (Pepsinogen) · Parietal cells (Gastric acid, Intrinsic factor) · Goblet cells (Mucus) Processes Swallowing · Vomiting Fluids Saliva · Gastric juice Lower GI Enteric nervous system Meissner's plexus · Auerbach's plexus Endocrine/paracrine G cells (gastrin) · D cells (somatostatin) · ECL cells (Histamine) enterogastrone: I cells (CCK) · K cells (GIP) · S cells (secretin) Enteroendocrine cells · Enterochromaffin cell · APUD cell Border Brunner's glands · Paneth cells · Enterocytes Fluids Intestinal juice Processes Segmentation contractions · Migrating motor complex · Borborygmus · Defecation Either/both Processes Peristalsis (Interstitial cell of Cajal) · Gastrocolic reflex · Digestion Accessory Fluids Bile · Pancreatic juice Processes Enterohepatic circulation Abdominopelvic Peritoneal fluid digestive system navs: anat of tract,glands,perit,diaphragm/physio/dev, noncongen/congen/congen of d+w/neoplasia, symptoms+signs/eponymous, proc

This digestive system article is a stub. You can help Wikipedia by expanding it. v • d • e