Aplasia (from Greek a—not; plésein—to form) is part of a heterogenous group of disorders first reported by Cordon in 1767 and is characterized by the absence of a portion of skin in a localized or widespread area at birth. It most commonly manifests as a solitary defect on the scalp, but sometimes it may occur as multiple lesions. The lesions are noninflammatory and well demarcated, and they range in size from 0.5-10 cm.^[1] ACC may be circular, oval, linear, or stellate in configuration. At birth, the lesions may have already healed with scarring or may remain superficially eroded to deeply ulcerated, occasionally involving the dura or the meninges.

[edit] Examples

• Aplastic anemia
• Acquired pure red cell aplasia
• Thymic aplasia

[edit] See also

• Atrophy
• Hyperplasia
• Hypoplasia
• Neoplasia

[edit] References

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