Annapolis, Nova Scotia can refer to:

• Annapolis Royal, Nova Scotia, a historic town, former colonial capital of Nova Scotia and currently the county seat for Annapolis County
• Annapolis County, Nova Scotia, one of Nova Scotia's 18 counties
• Annapolis River, a river running through the western part of the Annapolis Vally
• Annapolis Valley, a valley situated in northwestern Nova Scotia along the Bay of Fundy famous for its scenery and agricultural products
• Annapolis Basin, a sub-basin of the Bay of Fundy into which the Annapolis River discharges
• HMCS Annapolis, the name for two separate Canadian warships named after this part of Nova Scotia

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