Amoeba (sometimes amœba or ameba, plural amoebae) is a genus of protozoan, and may also refer to members of that genus. Amoeba can also refer to:

• an Amoeboid organism
• Amoeba distributed operating system
• Amoeba Music, an independent music chain
• Rogue Amoeba, a software company
• Amoeba (mathematics), a certain type of set
• Amoeba (band), an experimental music group with Robert Rich and Rick Davies
• Advanced Multiple Organized Experimental Basin (AMOEBA), a device that can form letters in a pool of water
• The contemporary British Poet, John Hegley, has a poem entitled Amoeba.
• The Adolescents have a song titled "Amoeba"
• Jon Scieszka's book, Science Verse, had a poem called Amoeba
• A code word used by asexuals to refer to themselves, such as in the slogan of the asexual community, "Asexuality: it's not just for amoebas anymore".

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