Aetius or Aëtius may refer to:

• Aetius (philosopher), 1st-century B.C. peripatetic philosopher
• Aëtius of Antioch, 4th-century Anomean theologian, called "Aetius the Atheist" by his Trinitarian enemies
• Flavius Aetius, 5th-century Roman general
• Aëtius Amidenus, 6th-century Byzantine physician
• Sicamus Aëtius, Byzantine medical writer possibly identical with the preceding

The Italian form is Ezio

Aetius (spider) is also a spider genus (Corinnidae)

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