Activator may mean:

• Activator (genetics), a DNA-binding protein that regulates one or more genes by increasing the rate of transcription
• Activator (proteomics), a type of effector that increases the rate of enzyme mediated reactions
• Sega Activator, a motion-sensing controller for the Sega Mega Drive/Genesis
• Activator technique, a method of spinal adjustment
• Activator, a hardcore band from Brooklyn, New York.

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