Aceclidine
Systematic (IUPAC) name
1-azabicyclo[2.2.2]oct-3-yl acetate
Identifiers
CAS number	827-61-2 6109-70-2 (HCl)
ATC code	S01EB08
PubChem	1979
ChemSpider	1902
Chemical data
Formula	C9H15NO2
Mol. mass	169.221 g/mol
SMILES	eMolecules & PubChem
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	Ocular

Aceclidine (INN) (trade names Glaucostat, Glaunorm, Glaudin) is a parasympathomimetic miotic agent used in the treatment of narrow angle glaucoma. It decreases intraocular pressure.

[edit] Adverse effects

Side effects of aceclidine include increased salivation, bradycardia (in excessive doses).

[edit] Mechanism of action

Aceclidine acts primarily on the muscarinic receptor.^[1]

[edit] References

1. ^ Shannon HE, Hart JC, Bymaster FP, et al (August 1999). "Muscarinic receptor agonists, like dopamine receptor antagonist antipsychotics, inhibit conditioned avoidance response in rats". J. Pharmacol. Exp. Ther. 290 (2): 901–7. PMID 10411607, http://jpet.aspetjournals.org/cgi/pmidlookup?view=long&pmid=10411607. 

• ACECLIDINE CHLORHYDRATE [Article in French] Biam. Last update: 2 September 1999. Accessed 13 September 2005 (UTC)
• ACECLIDINE (АЦЕКЛИДИН) [Article in Russian] ViDAL 2005. Accessed 13 September 2005.

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