ADPRHL2 Information & ADPRHL2 Links at HealthHaven.com

ADP-ribosylhydrolase like 2
	; PDB rendering based on 2foz.
Available structures
	2foz, 2fp0, 2g4k
Identifiers
Symbols	ADPRHL2; ARH3; FLJ20446; dJ665N4.2
External IDs	OMIM: 610624 MGI: 2140364 HomoloGene: 9863 GeneCards: ADPRHL2 Gene
Gene ontology
Gene ontology
Orthologs

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Poly(ADP-ribose) glycohydrolase ARH3 is an enzyme that in humans is encoded by the ADPRHL2 gene.^[1]^[2]^[3]

[edit] References

^ Glowacki G, Braren R, Firner K, Nissen M, Kuhl M, Reche P, Bazan F, Cetkovic-Cvrlje M, Leiter E, Haag F, Koch-Nolte F (Jun 2002). "The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse". Protein Sci 11 (7): 1657-70. doi:10.1110/ps.0200602. PMID 12070318.
^ Oka S, Kato J, Moss J (Jan 2006). "Identification and characterization of a mammalian 39-kDa poly(ADP-ribose) glycohydrolase". J Biol Chem 281 (2): 705-13. doi:10.1074/jbc.M510290200. PMID 16278211.
^ "Entrez Gene: ADPRHL2 ADP-ribosylhydrolase like 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54936.

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Kernstock S, Koch-Nolte F, Mueller-Dieckmann J, et al. (2006). "Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of human ARH3, the first eukaryotic protein-ADP-ribosylhydrolase.". Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62 (Pt 3): 224–7. doi:10.1107/S1744309106003435. PMID 16511307.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
Mueller-Dieckmann C, Kernstock S, Lisurek M, et al. (2006). "The structure of human ADP-ribosylhydrolase 3 (ARH3) provides insights into the reversibility of protein ADP-ribosylation.". Proc. Natl. Acad. Sci. U.S.A. 103 (41): 15026–31. doi:10.1073/pnas.0606762103. PMID 17015823.
Ono T, Kasamatsu A, Oka S, Moss J (2006). "The 39-kDa poly(ADP-ribose) glycohydrolase ARH3 hydrolyzes O-acetyl-ADP-ribose, a product of the Sir2 family of acetyl-histone deacetylases.". Proc. Natl. Acad. Sci. U.S.A. 103 (45): 16687–91. doi:10.1073/pnas.0607911103. PMID 17075046.

This article on a gene on chromosome 1 is a stub. You can help Wikipedia by expanding it.

[pmid12070318-0] Glowacki G, Braren R, Firner K, Nissen M, Kuhl M, Reche P, Bazan F, Cetkovic-Cvrlje M, Leiter E, Haag F, Koch-Nolte F (Jun 2002). "The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse". Protein Sci 11 (7): 1657-70. doi:10.1110/ps.0200602. PMID 12070318.

[pmid16278211-1] Oka S, Kato J, Moss J (Jan 2006). "Identification and characterization of a mammalian 39-kDa poly(ADP-ribose) glycohydrolase". J Biol Chem 281 (2): 705-13. doi:10.1074/jbc.M510290200. PMID 16278211.

[entrez-2] "Entrez Gene: ADPRHL2 ADP-ribosylhydrolase like 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54936.

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