ACAM2000 is a smallpox vaccine developed by Acambis. It was approved for use in the United States by the U.S. Food and Drug Administration (FDA) on 31 August 2007. It contains live vaccinia virus, cloned from the same strain used in an earlier vaccine, Dryvax. While the DryVax virus was cultured in the skin of calves and freeze-dried, ACAM2000's virus is cultured in kidney epithelial cells (Vero cells) from an African green monkey. Efficacy and adverse reaction incidence are similar to DryVax. The vaccine is not available to the US public; it is, however, used in the military and kept in the Strategic National Stockpile.^[1]

[edit] References

1. ^ FDA/CBER Questions and Answers; Medication Guide; accessed 1 March 2008.

[edit] External links

• FDA/CBER ACAM2000 Questions and Answers
• Package Insert
• Medication Guide

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