5,10-Methylenetetrahydrofolate Information & 5,10-Methylenetetrahydrofolate Links at HealthHaven.com

5,10-Methylenetetrahydrofolate

Identifiers
CAS number	3432-99-3
PubChem	108194
MeSH	5,10-methylenetetrahydrofolate
Properties
Molecular formula	C₂₀H₂₃N₇O₆
Molar mass	457.44 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

5,10-Methylenetetrahydrofolate (5,10-CH₂-THF, MTHF) is the substrate used by methylenetetrahydrofolate reductase (MTHFR) to generate 5-methyltetrahydrofolate (5-MTHF). 5,10-CH₂-THF is also a coenzyme used in thymidine biosynthesis by thymidylate synthase (FAD).

[edit] See also

v • d • e Enzyme cofactors

Active Forms	vitamins: TPP / ThDP (B₁) · FMN, FAD (B₂) · NAD⁺, NADH, NADP⁺, NADPH (B₃) · Coenzyme A (B₅) · PLP / P5P (B₆) · Biotin (B₇) · THFA / H₄FA, DHFA / H₂FA, MTHF (B₉) · AdoCbl, MeCbl (B₁₂) · Ascorbic Acid (C) · Phylloquinone (K₁, Menaquinone (K₂) · Coenzyme F420 non-vitamins: ATP · CTP · SAMe · PAPS · GSH · Coenzyme B · Coenzyme M · Coenzyme Q · Heme / Haem (A, B, C, O) · Lipoic Acid · Methanofuran · Molybdopterin · PQQ · THB / BH₄ · THMPT / H₄MPT minerals: Ca²⁺ · Cu²⁺ · Fe²⁺, Fe³⁺ · Mg²⁺ · Mn²⁺ · Mo · Ni²⁺ · Se · Zn²⁺

Base Forms	vitamins: Thiamine (B₁) · Riboflavin (B₂) · Niacin, Niacinamide (B₃) · Pantothenic Acid (B₅) · Pyridoxine, Pyridoxamine, Pyridoxal (B₆) · Cyanocobalamin, Hydroxocobalamin (B₁₂)

Major families of biochemicals Saccharides/Carbohydrates/Glycosides · Amino acids/Peptides/Proteins/Glycoproteins · Lipids/Terpenes/Steroids/Carotenoids · Alkaloids/Nucleobases/Nucleic acids · Cofactors/Phenylpropanoids/Polyketides/Tetrapyrroles

A	Retinol · β-Carotene · Tretinoin · α-Carotene

D	D₂ (Ergosterol, Ergocalciferol) · D₃ (7-Dehydrocholesterol, Previtamin D3, Cholecalciferol, 25-hydroxycholecalciferol, Calcitriol (1,25-dihydroxycholecalciferol), Calcitroic acid) D₄ (Dihydroergocalciferol) · D₅ · D analogues (Dihydrotachysterol, Calcipotriol, Tacalcitol, Paricalcitol)

E	Tocopherol (Alpha, Beta, Gamma, Delta) · Tocotrienol · Tocofersolan

K	Naphthoquinone · Phylloquinone/K1 · Menatetrenone/K2 · Menadione/K3

B	B₁ (Thiamine) · B₂ (Riboflavin) · B₃ (Niacin, Nicotinamide) · B₅ (Pantothenic acid, Dexpanthenol, Pantethine) · B₆ (Pyridoxine, Pyridoxal phosphate, Pyridoxamine) B₇ (Biotin) · B₉ (Folic acid, Dihydrofolic acid, Folinic acid) · B₁₂ (Cyanocobalamin, Hydroxocobalamin, Methylcobalamin, Cobamamide) · Choline

C	Ascorbic acid · Dehydroascorbic acid

see also: enzyme cofactors, enzymes, Multivitamins

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