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In enzymology, a 4-(hydroxymethyl)benzenesulfonate dehydrogenase (EC 1.1.1.257) is an enzyme that catalyzes the chemical reaction

4-(hydroxymethyl)benzenesulfonate + NAD⁺ 4-formylbenzenesulfonate + NADH + H⁺

Thus, the two substrates of this enzyme are 4-(hydroxymethyl)benzenesulfonate and NAD⁺, whereas its 3 products are 4-formylbenzenesulfonate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-(hydroxymethyl)benzenesulfonate:NAD+ oxidoreductase. This enzyme participates in 2,4-dichlorobenzoate degradation.

[edit] References

• Cook AM (Pt 9). "Degradative pathways for p-toluenecarboxylate and p-toluenesulfonate and their multicomponent oxygenases in Comamonas testosteroni strains PSB-4 and T-2". Microbiology. 142: 2419–27. PMID 8828208.