1,3-Difluoro-2-propanol
IUPAC name	1,3-Difluoro-2-propanol
Identifiers
CAS number	453-13-4
PubChem	67985
SMILES	C(C(=O)N)F
Properties
Molecular formula	C3H6F2NO
Molar mass	110.08 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

1,3-Difluoro-2-propanol is a metabolic poison which disrupts the citric acid cycle and is used as a rodenticide, similar to sodium fluoroacetate. It is the main ingredient (along with 1-chloro-3-fluoro-2-propanol) in the rodenticide product Gliftor which was widely used in the former USSR.^[1][2][3]

[edit] References

1. ^ Buklan AI, Kravets AF (1986). "[Gliftor poisoning]" (in Russian). Sud. Med. Ekspert. 29 (1): 55–6. PMID 3961873. 
2. ^ Feldwick MG, Noakes PS, Prause U, Mead RJ, Kostyniak PJ (1998). "The biochemical toxicology of 1,3-difluoro-2-propanol, the major ingredient of the pesticide gliftor: the potential of 4-methylpyrazole as an antidote". J. Biochem. Mol. Toxicol. 12 (1): 41–52. doi:10.1002/(SICI)1099-0461(1998)12:1<41::AID-JBT6>3.0.CO;2-P. PMID 9414486. 
3. ^ Menon KI, Feldwick MG, Noakes PS, Mead RJ (2001). "The mode of toxic action of the pesticide gliftor: the metabolism of 1,3-difluoroacetone to (-)-erythro-fluorocitrate". J. Biochem. Mol. Toxicol. 15 (1): 47–54. doi:10.1002/1099-0461(2001)15:1<47::AID-JBT6>3.0.CO;2-E. PMID 11170315. 

v • d • e Pest control: rodenticides Anticoagulants/ vitamin K antagonists coumarins/4-Hydroxycoumarins: 1st generation (Warfarin, Coumatetralyl) • 2nd generation (Brodifacoum, Difenacoum, Flocoumafen) 1,3-Indandiones: Chlorophacinone • Pindone • Diphacinone other: Difethialone Convulsants Crimidine • Phenylsilatrane • Strychnine • Tetramethylenedisulfotetramine Calciferols Cholecalciferol • Ergocalciferol Inorganic compounds Aluminium phosphide • Arsenic • Barium carbonate • Calcium phosphide • Cyanide • Thallium • Zinc phosphide Organochlorine Chloralose • Endrin Organophosphorus Phosacetim Metabolic poisons Bromethalin • Fluoroacetamide • 1,3-Difluoro-2-propanol (Gliftor) • Sodium fluoroacetate Other α-Naphthylthiourea • Norbormide • Pyrinuron • Scilliroside

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