(R)-3-amino-2-methylpropionate-pyruvate transaminase Information & (R)-3-amino-2-methylpropionate-pyruvate transaminase Links at HealthHaven.com

(R)-3-amino-2-methylpropionate-pyruvate transaminase
Identifiers
EC number	2.6.1.40
CAS number	37279-00-8
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	structures
Gene Ontology	AmiGO / EGO
Search
PMC	articles
PubMed	articles

In enzymology, a (R)-3-amino-2-methylpropionate-pyruvate transaminase (EC 2.6.1.40) is an enzyme that catalyzes the chemical reaction

(R)-3-amino-2-methylpropanoate + pyruvate $\rightleftharpoons$ 2-methyl-3-oxopropanoate + L-alanine

Thus, the two substrates of this enzyme are (R)-3-amino-2-methylpropanoate and pyruvate, whereas its two products are 2-methyl-3-oxopropanoate and L-alanine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is (R)-3-amino-2-methylpropanoate:pyruvate aminotransferase. Other names in common use include D-3-aminoisobutyrate-pyruvate transaminase, beta-aminoisobutyrate-pyruvate aminotransferase, D-3-aminoisobutyrate-pyruvate aminotransferase, D-3-aminoisobutyrate-pyruvate transaminase, (R)-3-amino-2-methylpropionate transaminase, and D-beta-aminoisobutyrate:pyruvate aminotransferase.

[edit] References

Kakimoto Y, Taniguchi K, Sano I (1969). "D-beta-aminoisobutyrate:pyruvate aminotransferase in mammalian liver and excretion of beta-aminoisobutyrate by man". J. Biol. Chem. 244: 335–40. PMID 5773299.
Tamaki N, Sakata SF, Matsuda K (2000). "Purification, properties, and sequencing of aminoisobutyrate aminotransferases from rat liver". Methods. Enzymol. 324: 376–89. doi:10.1016/S0076-6879(00)24247-X. PMID 10989446.

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